Validation of the Brazilian version of the hepatitis B quality of life evaluation instrument - HBQOL, and its application to patients with chronic hepatitis B in Cascavel - PR

Abstract The objective of this study is to validate the specific questionnaire for Hepatitis B HBQOL (Hepatitis B Quality of Life Instrument, version 1.0) for the Brazilian version, in addition to testing its applicability in patients with hepatitis B under treatment and comparing the quality of life between patients using first-line drugs (tenofovir and entecavir). For the validation, the back-translation technique was used in a sample of 47 patients. Factor analysis was performed between the items in each domain of the questionnaire and the internal consistency was calculated using Cronbach's α coefficient. In assessing the applicability of the validated questionnaire, interviews were carried out with 124 patients. Sociodemographic and treatment data were collected to characterize the sample and perform correlation analyzes. The results demonstrate that the Brazilian version of the questionnaire was successfully validated. In the analysis carried out among the 124 patients, the domains psychological well-being and stigma obtained the highest scores in quality of life and the lowest level of education conferred better results in these two domains. The comparison between tenofovir and entecavir showed no significant difference in patients' quality of life. The use of this validated instrument can make therapeutic decisions more rational

Comparison of two oral health-related quality-of-life measures in elderly patients: the influence of missing teeth, and socio demographic factors / Comparação entre dois instrumentos de avaliação de qualidade de vida em pacientes idosos: a influência da perda de dentes e fatores sociodemográficos

Objective: The Oral Health Impact Profile-14 (OHIP14) and the Geriatric/General Oral Health Assessment Index (GOHAI) have never been compared to a group of the same subjects in the Brazilian population. The aim of the study was to compare the OHIP-14 and GOHAI measures. Material and Methods: 129 independently living people over the age of 60 were included in the study. The GOHAI and OHIP-14 measures were used. Other variables were included: age, gender, education, number of missing teeth, annual household income and frequency of dentist visits. Results: The mean age of respondents was 65 years. The internal reliability (Cronbach's alpha) showed a high internal consistency for both measures. Spearman's rank correlation coefficient between the GOHAI and OHIP-14 scores was 0.73. Using the additive method of creating scores, none of the respondents had the GOHAI score of zero, indicating no impact from oral conditions, while 9.3% of them had an OHIP-14 score of zero. Dental status, age, gendler and frequency of dental visit were significantly associated with the results ofthe GOHAI and the OHIP-14 (Kruskal­Wallis test, Mann­Whitney U test). Conclusions: There was a strong correlation between the GOHAI and the OHIP14. Both instruments demonstrated good discriminant properties and helped capture the respondents' oral health problems. (AU)

Objetivo: O Perfil de Impacto na Saúde Oral-14 (OHIP14) e o Índice Geral de Avaliação de Saúde Oral em Geriatria (GOHAI) nunca foram comparados a um grupo dos mesmos sujeitos na população brasileira. O objetivo do estudo foi comparar as medidas OHIP-14 e GOHAI. Material e Métodos: 129 pessoas independentes com idade superior a 60 anos foram incluídas no estudo. Foram utilizadas as medidas GOHAI e OHIP-14. Outras variáveis foram incluídas: idade, sexo, escolaridade, número de dentes ausentes, renda familiar anual e frequência de visitas ao dentista. Resultados: a média de idade dos entrevistados foi de 65 anos. A confiabilidade interna (alfa de Cronbach) mostrou uma alta consistência interna para ambas as medidas. O coeficiente de correlação de Spearman entre os escores GOHAI e OHIP-14 foi de 0,73. Utilizando o método aditivo de criação de escores, nenhum dos entrevistados obteve pontuação zero no GOHAI, indicando nenhum impacto das condições bucais, enquanto 9,3% deles tiveram pontuação zero no OHIP-14. O estado dentário, a idade, o sexo e a frequência da visita foram significativamente associados aos resultados do GOHAI e do OHIP-14 (teste de Kruskal-Wallis, teste de Mann-Whitney U). Conclusões: Houve uma forte correlação entre o GOHAI e o OHIP-14. Ambos os instrumentos demonstraram boas propriedades discriminantes e ajudaram a capturar os problemas de saúde bucal dos entrevistados. (AU)